The purpose of this new imaging method is to provide physicians with additional information
not available with standard imaging methods. This includes information about the make up of
different breast diseases. Using spectroscopy data, it may be possible to tell the
difference between benign conditions of the breast from malignant tumors and provide more
accurate information than can be obtained with regular MRI. Along with the MRI a new method
of evaluating the images or pictures will be used. This new method is called spectroscopy
and is used routinely on other parts of the body such as the prostate and brain. Pictures
produced with this sequence look different than the regular MRI pictures. Performing
spectroscopy on a 1.5T magnet adds another imaging sequence (another scan) to the routine
MRI protocol, thus increasing exam time (extra 10-15 minutes). This study will enroll
patients who are scheduled for a Magnetic Resonance Imaging (MRI) examination ordered by
their primary physician.
Our aim is to perform MR Spectroscopy (MRS) on 150 patients at the end of their clinically
indicated routine breast MRI guided biopsy and breast MRI guided needle localization
examination using a software package from General Electric Medical Systems (Milwaukee,WI).
This will add time to the routine examination but will not involve additional injections of
contrast. We will analyze the spectroscopic data to determine if benign lesions can be
reliably differentiated from malignant ones. The MR Spectroscopy (MRS) will be administered
at Memorial Sloan Kettering Cancer Center, 1275 York Ave, NY,NY 10021.
- Patient needs to be ≥ or = to 18 years of age
- scheduled for diagnostic breast MRI examination or interventional procedure for a
suspected or known breast lesion ≥ or = to 1 centimeter
- Patients who would be normally excluded from undergoing an MRI examination include:
- Patients with a pacemaker, aneurysm clip or any other condition that would warrant
avoidance of a strong magnetic field
- Patients who are pregnant are excluded from participation of this study
- Patients who are unable to comply or complete the MRI exam due to claustrophobia or
high levels of anxiety.
- Patients undergoing chemotherapy