Expired Study
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Lexington, Kentucky 40506


This study will evaluate a handheld event-related potential (ERP) testing device from Neuronetrix, Inc. as a method to collect ERP data in an outpatient setting. An ERP system records electrical signals at the scalp that are produced by the brain when performing cognitive tasks. By doing this study, we hope to evaluate various performance parameters of the COGNISION(TM) system.

Study summary:

Patients who have a current diagnosis of mild-moderate dementia and suspected of having Alzheimer's disease (AD) along with cognitively normal age-matched controls will be recruited for this study. The Alzheimer's subjects either will have had a complete clinical and neuropsychiatric workup or will have those tests performed during the study. Both groups, AD and controls will be asked to listen to a series of sounds and press a button on a handheld control box when a target sound is heard. The COGNISION(TM) headset on each subject's head will then record the electrical signals during this task. Four important features of the COGNISION(TM) will be investigated: 1. Patient tolerance 2. Ease of use 3. Data quality 4. Network architecture


Inclusion Criteria for AD: - Age 60 to 85 - Mild to moderate diagnosis of Alzhiemer's disease Inclusion Criteria for Control: - Age 60 to 85 - Cognitively healthy with no complaints Exclusion Criteria: - Subjects with advanced AD and severe impairment (CDR > 2, MMSE less than 15) - Neurological disorders such as stroke, Parkinson's disease, Huntington's disease, multiple sclerosis, brain tumor, delirium, or psychiatric disorder other than depression (e.g. schizophrenia) - Subjects with life threatening illnesses and subjects with significant hearing or visual impairments - Subjects with a current prescription for psychoactive pharmaceuticals



Primary Contact:

Principal Investigator
Charles D Smith, M.D.
University of Kentucky

Backup Contact:


Location Contact:

Lexington, Kentucky 40506
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: March 16, 2018

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