Expired Study
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Omaha, Nebraska 68105


To detect coronary artery disease by both coronary and carotid artery imaging and myocardial perfusion imaging using a new low mechanical index real time system.

Study summary:

The objective of this clinical study will be to visualize both coronary and carotid arteries as well as detect myocardial perfusion following a routine intravenous injection of Definity (0.05-0.20 millimeters), Optison (0.1-0.4 millimeters) or PESDA (0.05-0.2 mL). Following these injections , we will attempt to Contrast Pulse Sequencing on the Siemens Acuson Sequoia system to image both the coronary and carotid arteries, as well as the Myocardial perfusion.


Inclusion Criteria: - subjects scheduled for routine echocardiogram to look for evidence of Coronary artery disease or a stress echocardiogram - women of child-bearing potential must be taking a medically approved form of birth control with a negative urine pregnancy test - be conscious and coherent, and be able to communicate effectively with study personnel - last eight patients will be diabetics who smoke - provide informed consent after receiving a verbal and written explanation of the purpose and nature of the study Exclusion Criteria: - severe valvular heart disease by Doppler Echocardiography - females of child-bearing potential who are not taking a medically approved method of birth control will be excluded. If the patient is pregnant she will be excluded. - patients who are allergic to blood or blood products will be excluded - have contraindication to Optison, Definity, or PESDA (pulmonary HTN, cardiac shunt) - non diabetics, non smokers



Primary Contact:

Principal Investigator
Thomas R Porter, MD
University of Nebraska

Backup Contact:


Location Contact:

Omaha, Nebraska 68105
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: March 16, 2018

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