The purpose of this study is to help us learn more about the roles of genes in cancers. Genes
are short pieces of DNA which determine the inherited characteristics that distinguish one
individual from another. This study will look at how some genes might raise or lower the
chance some people may develop cancer. The sample collection will help generate the materials
needed for this study.
This is a protocol to obtain saliva or blood samples from non-cancer affected volunteers aged
60 years or older, without a history of cancer other than non-melanoma skin cancer. These
samples will be used in a genomic approach to elucidate novel pathways of cancer
- Eligible subjects must be non-cancer affected volunteers of either gender who are 60
years of age or older at the time of saliva/blood donation.
- Subjects will self-identify religion and country of origin of grandparents.
- Volunteers will have (by self report) no history of cancer other than nonmelanoma skin
cancer. It is recognized that there may be some errors in self report, however, the
literature reports a very low error rate for self reported disease reporting for
cancer as assessed by interview.
- Subjects with mental impairment will be excluded from this study.