To Determine whether transcranial ultrasound can detect the presence of intravenously
injected microbubbles used routinely for dobutamine stress echocardiography.
The purpose of this study is to determine whether the intravenous microbubbles used to
improve border delineation during dobutamine stress echocardiographies (DSE) can be detected
within the cerebral circulation.
- male or female age >19 years of age
- scheduled for a stress echocardiogram
- negative urine pregnancy test within two hours of ultrasound contrast administration
required for females of childbearing age unless post-menopausal or with evidence of
- be conscious and coherent, and able to communicate effectively with trial personnel
- pregnant or lactation
- life expectancy of less than 2 months or terminally ill
- Known or suspected hypersensitivity to ultrasound contrast agent used for the study
- complicated hemodynamic instability
- Known left main disease