This research study is designed to evaluate the accuracy of the techniques that are used to
analyze heart function. The main purpose of this study is to analyze and compare three
different methods of assessment of regional and overall heart function.
The purpose of the present study is to establish the reproducibility and to validate gated
blood pool SPECT imaging with application of attenuation correction (ACGBS) in evaluation of
left ventricular regional and global function and volumes, by direct comparison with
Equilibrium Radionuclide Angiocardiography (ERNA) and 3-dimensional ECHO (3DE).
- All patients scheduled for routine clinically requested ERNA study for ejection
fraction measurement at the Yale University Cardiovascular Nuclear Imaging Laboratory
are eligible to be enrolled in the study.
- Unstable medical condition preventing additional imaging.
- Weight greater than 300lbs, prohibiting imaging on the SPECT/CT imaging system.
- Patients with intracardiac shunts, emphysema or previously demonstrated allergies to
octafluoropropane (the gas in the microbubbles), will not receive intravenous
contrast during 3 DE image acquisition.