Expired Study
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Los Angeles, California 90033


Purpose:

Patients with bleeding ulcers identified by endoscopy will be randomly assigned to receive an acid-blocking drug (called a proton pump inhibitor [PPI]) either by mouth every 3 hours for 24 hours or intravenously (IV) by constant infusion for 24 hours. A pH probe in the stomach will be used to determine intragastric pH (a measure of the acid production in the stomach) at baseline and during the 24 hours of therapy. The purpose of the study is to determine if the continuous intravenous administration of the drug provides better reduction of acid in the stomach than the oral administration.


Criteria:

Inclusion Criteria: - Patients presenting to hospital with overt upper GI bleeding and found to have an ulcer as the cause on endoscopy Exclusion Criteria: - Previous gastric surgery - Active bleeding at end of endoscopy (despite hemostatic therapy) - Recent PPI or H2RA use


NCT ID:

NCT00573924


Primary Contact:

Principal Investigator
Loren Laine, M.D.
University of Southern California


Backup Contact:

N/A


Location Contact:

Los Angeles, California 90033
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: August 17, 2017

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