Expired Study
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Omaha, Nebraska 68198


Purpose:

To determine the response rate, complete and partial, of patients with indolent lymphoma receiving Rituxan and BEAM with autologous stem cell transplant.


Study summary:

Objectives: I. To determine the response rate, complete and partial, of patients with indolent lymphoma receiving Rituxan and BEAM with autologous stem cell transplant. II. To determine if the addition of Rituxan changes the toxicity profile attributed to high-dose BEAM chemotherapy. This protocol is a phase I/II trial combining the Rituxan as a pre and post-transplant agent to aid in the chemotherapy sensitization and the treatment of minimal residual disease post-transplant.


Criteria:

Inclusion Criteria: - Any low-grade B-cell, CD20 positive, non-Hodgkin's lymphoma that is felt to otherwise be a transplant candidate (relapsed, induction failure, first PR or CR). Specifically: Small lymphocytic, marginal zone, mantle cell, and follicular histologies. - At least 19 years of age - Signed written informed consent - Expected survival of at least 6 months - Subjects with out history of T-cell lymphoma - WHO performance status greater or equal to 2 - Subjects without serious disease or condition that, in the opinion of the investigator, would compromise the subject's ability to participate in the study. - Non-pregnant and non-lactating women - Male or female subjects of reproductive potential who are able to follow accepted birth control measures.


NCT ID:

NCT00572013


Primary Contact:

Principal Investigator
Julie M Vose, M.D.
University of Nebraska


Backup Contact:

N/A


Location Contact:

Omaha, Nebraska 68198
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: March 16, 2018

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