Huntersville, North Carolina 28078


Purpose:

Primary Objective: This is a study to investigate the feasibility of harvesting, expanding in culture, and freezing circulating tumor cells and immune cells from cancer patients and healthy volunteers.


Criteria:

Inclusion Criteria: - Histological diagnosis of metastatic stage IV or locally advanced (unresectable) stage III cancer of any solid tumor type. Patients may have been previously treated or chemo naïve or healthy volunteer - Age > 18yo - Life expectancy > 12 weeks - ECOG Performance Status of 0, 1, 2, or 3 (Appendix 2) - Screening laboratory values must meet the following criteria: - WBC ≥2000/µL - Neutrophils ≥1500/µL - Platelets >100x103/µL - Hemoglobin ≥8 g/dL - Creatinine <2.5 x ULN - AST ≤2.5 x ULN without, and ≤ 5 x ULN with hepatic metastases - Bilirubin ≤2 x ULN (except patients with Gilbert's syndrome, who must have total bilirubin < 3.0 mg/dL) Exclusion Criteria: - Primary Hematologic Malignancies (leukemia, lymphoma) - Patients with any active infection requiring therapy (fever, localizing source) will be excluded until the infection resolves. - History of, or a positive test for HIV-1, HIV-2, or HTLV-1 serum antibody, hepatitis B surface antigen, or hepatitis C positive RNA - Underlying medical condition that, in the Principal Investigator's or treating oncologist's opinion, will obscure the interpretation of the patient's safety.


NCT ID:

NCT00571389


Primary Contact:

Principal Investigator
John Powderly, M.D.
Carolina BioOncology Institute

John Powderly, M.D.
Phone: 704-947-6599
Email: jpowderly@carolinabiooncology.org


Backup Contact:

N/A


Location Contact:

Huntersville, North Carolina 28078
United States

Amanda Balasco, CCRC
Phone: 704-947-6599
Email: abalasco@carolinabiooncology.org

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: November 19, 2017

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