Expired Study
This study is not currently recruiting Study Participants on ClinicalConnection.com. If you would like to find active studies please search for clinical trials.

Philadelphia, Pennsylvania 19104


Purpose:

The purpose of this study is to determine the effect of rosiglitazone on the genes of the colon


Study summary:

The primary aim of the study is to examine the effect of rosiglitazone (Avandia) on gene regulation in colonic epithelium in the absence of pathologic acute and chronic intestinal inflammation. The secondary aims are to determine the effect of rosiglitazone (Avandia) therapy on T cell activation and cytokine expression in the absence of pathologic acute and chronic intestinal inflammation.


Criteria:

Inclusion Criteria: - Capable of giving informed consent - Agrees to use a barrier method of birth control for the duration of the study Exclusion Criteria: - History of inflammatory bowel disease - Has taken prescription or over the counter medications in the two weeks prior to enrollment - History of diabetes, heart failure, angina, hypertension, coronary heart disease, cancer, bleeding disorder, HIV, AIDS - Fasting LDL >160 mg/dl - History of smoking in the year prior to enrollment - Pregnant or breastfeeding


NCT ID:

NCT00567593


Primary Contact:

Principal Investigator
James D Lewis, MD, MSCE
University of Pennsylvania


Backup Contact:

N/A


Location Contact:

Philadelphia, Pennsylvania 19104
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: November 17, 2017

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.


Click to view Full Listing

This study is not currently recruiting Study Participants on ClinicalConnection.com. The form below is not enabled.