New Hyde Park,
The investigators hypothesize that baseline plasma brain natriuretic peptide (BNP) and
migration inhibitory factor (MIF) levels are surrogate markers of clinical severity of PAH
and that changes in plasma brain natriuretic peptide (BNP) and MIF levels pre and post
- Confirmed diagnosis of PAH, based on currently accepted gold standard for Right Heart
- Patients with mean artery pressure of greater that 25 mm Hg at rest or 30mm Hg during
exercise with pulmonary capillary wedge pressure less than 18mm Hg on right heart
- Significant left heart disease or renal insufficiency (serum creatinine > 1.5 mg%).