The purpose of this study is to determine the concentration of omega-3 fatty acids in
plasma, blood and abdominal fat before and after bariatric surgery to provide guidance for
The omega-3 fatty acids are essential for human growth, development and well-being. Numerous
studies have shown that a relatively high intake of the omega-3 fatty acids are beneficial
in brain and visual development, psychiatric disorders, rheumatic disorders, inflammatory
responses and cardiovascular disease. As an example, low levels of tissue omega-3 fatty
acids are associated with a markedly higher rate of death from cardiac causes compared to
patients with relatively high concentrations of the omega-3 fatty acids. Obese patients
often have an unhealthy dietary intake and evidence of increased inflammatory processes.
After a gastric bypass patients will have decreased absorption of fats from the
gastrointestinal tract and may become fatty acid deficient. While gastric bypass may
decrease death from cardiovascular disease in morbidly obese patients, cardiovascular
disease is still the most common cause of death after a gastric bypass. There are numerous
nutritional deficiencies which occur after gastric bypass and many of these are well
documented. However, there are no data concerning the plasma and tissue levels of omega-3
fatty acids in morbidly obese patients either before or after operation.
- Surgical group candidates must be undergoing surgery for morbid obesity,
abdominoplasty or other abdominal operation.
- Must have adequate venous access.
- Insufficient venous access