Expired Study
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Cleveland, Ohio 44106


Purpose:

The purpose of this study is to evaluate the immune response to a routine influenza vaccination. Influenza vaccination is given as part of routine standard of care in these individuals and is not part of the study protocol. The study will evaluate for a change in response to common antigens over time after influenza vaccination to determine if changes are related to the development of chronic rejection after solid-organ transplantation. We hypothesize that the influenza vaccine contributes to the alloreactivity of T cells verses common HLA types in the donor pool.


Criteria:

Inclusion Criteria: - Transplant recipients (lung or kidney) 18 years or older, more than 3 months after transplantation - Transplant candidates (kidney) 18 years or older, to recieve influenza vaccination - Healthy volunteers to receive influenza vaccination Exclusion Criteria: - Under 18 years of age - Pregnant - Medical contraindication for vaccine - Transplant recipients receiving acute rejection therapy within one month - Healthy volunteers with autoimmune disease or medications to mediate immune function - Receipt of live, attenuated influenza vaccine, instead of injectable vaccine


NCT ID:

NCT00551837


Primary Contact:

Study Director
Emilio Poggio, MD
The Cleveland Clinic


Backup Contact:

N/A


Location Contact:

Cleveland, Ohio 44106
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: August 22, 2017

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