Expired Study
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East Hanover, New Jersey 07936


Purpose:

This study is a proof of efficacy dose ranging study in patients with essential hypertension to assess the blood pressure lowering effect, and safety of LCZ696 compared to valsartan and placebo. The study will also evaluate the efficacy and safety of AHU377 as compared to placebo.


Criteria:

Inclusion Criteria: - Willing to sign informed consent - Male and females from 18 up to 75 years inclusive Mild-to-moderate uncomplicated essential hypertension Medication compliance ≥80 % compliance rate during the run-in period Exclusion Criteria: - Severe hypertension (MSSBP ≥180 mmHg and/or MSDBP ≥110 mmHg) - Women of child-bearing potential (WOCBP) unless they are post-menopausal or use predefined acceptable methods of contraception - History of angioedema, drug-related or otherwise, as reported by the patient - Type 1 or Type 2 diabetes mellitus (according to the ADA criteria) - History of angina pectoris, myocardial infarction, coronary bypass surgery, ischemic heart disease, surgical or percutaneous arterial intervention of any kind (coronary, carotid or peripheral intervention), stroke, TIA (transient ischemic attack), carotid artery stenosis, aortic aneurysm or peripheral arterial disease Other protocol-defined inclusion/exclusion criteria may apply


NCT ID:

NCT00549770


Primary Contact:

Study Chair
Novartis Pharmaceuticals
Novartis Pharmaceuticals


Backup Contact:

N/A


Location Contact:

East Hanover, New Jersey 07936
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: November 21, 2017

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