Expired Study
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San Antonio, Texas 78229


Purpose:

Genasense® is currently administered to subjects in clinical studies as a multiple-day continuous intravenous infusion. Subjects are treated on an outpatient basis and carry a pump that delivers the drug through a peripheral or central intravenous line. The route of administration limits the convenience of treatment, and catheter-related complications have been reported. This study is designed to evaluate the pharmacokinetics and safety of G3139 administered by subcutaneuous injection.


Criteria:

Inclusion Criteria: - A Confirmed diagnosis of a solid tumor malignancy, not to include lymphoma, that has failed standard therapy or for which no standard therapy is available. Patients with a history of brain metastasis will be eligible if there is no evidence of cerebral edema or treatment with steroids. - Adequate organ function as determined < 7 days prior to starting study medication - Eastern Cooperative Oncology Group (ECOG) performance status 0 to 2 - At least 3 weeks and recovery from effects of major prior surgery or other therapy including radiation therapy, immunotherapy, cytokine, biological, vaccine and chemotherapy Exclusion Criteria: - Significant medical diesese - History of leptomeningeal disease - Coexisting condition that would require the subject to continue therapy during the treatment phase of the study with a drug known to alter renal function. - Use of any investigational drug within 3 weeks prior to starting study medication - Known hypersensitivity to phosphorothioate-containing oligonucleotides - Pregnancy/Lactation


NCT ID:

NCT00543231


Primary Contact:

N/A


Backup Contact:

N/A


Location Contact:

San Antonio, Texas 78229
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: August 22, 2017

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