Expired Study
This study is not currently recruiting Study Participants on ClinicalConnection.com. If you would like to find active studies please search for clinical trials.

Boston, Massachusetts 02215


Purpose:

The purpose of this study is to determine whether a painless and noninvasive procedure called transcranial direct current stimulation (tDCS) combined with a method of physical therapy called constraint-induced movement therapy improves motor function in patients with chronic stroke. Research in healthy subjects has shown that when tDCS is combined with motor learning tasks, there is an increase in learning as compared to motor learning tasks only. The tDCS procedure sessions will be compared to sham (fake) procedure sessions, which is also called placebo stimulation. This study is double blind, which means neither the subjects nor researchers analyzing motor function will know if participants are receiving real tDCS stimulation or placebo. Only the person performing the procedure will know which one participants are receiving. Only by comparing the tDCS procedure to a sham (placebo) procedure can we understand if the tDCS actually improves motor function. We hypothesize that tDCS will enhance the effects of constraint-induced movement therapy on motor recovery in chronic stroke patients.


Criteria:

Inclusion Criteria: - First time clinical ischemic or hemorrhagic cerebrovascular accident (radiologically confirmed) - Demonstrates adequate balance while wearing a hand restraint on the unaffected arm - Ability to stand from a sitting position and ability to stand with or without upper extremity support - Stroke onset at least 6 months prior to study enrollment Exclusion Criteria: - Significant pre-stroke disability - Any substantial decrease in alertness, language reception, or attention that might interfere with understanding instructions for motor testing - Excessive pain in any joint of the paretic extremity - A terminal medical diagnosis consistent with survival of less than 1 year - Advanced liver, kidney, cardiac, or pulmonary disease - Coexistent major neurological or psychiatric disease (including epilepsy) - A history of significant alcohol or drug abuse in the prior 3 years - Use of neuropsychotropic drugs - such as antidepressants - Patients may not be actively enrolled in a separate intervention study targeting stroke recovery - Patients may not have already received constraint-induced movement therapy and/or tDCS treatment for stroke


NCT ID:

NCT00542256


Primary Contact:

Principal Investigator
Felipe Fregni, MD, PhD
Beth Israel Deaconess Medical Center

Julie A Williams, M.Sc.
Phone: 617-667-5261
Email: jawillia@bidmc.harvard.edu


Backup Contact:

N/A


Location Contact:

Boston, Massachusetts 02215
United States



There is no listed contact information for this specific location.

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: August 16, 2017

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.


Click to view Full Listing

This study is not currently recruiting Study Participants on ClinicalConnection.com. The form below is not enabled.