This study is to compare the ability of optical biopsy. Research can use light enters the
skin, collected, analyzed by the computer, and a picture created for the pathologist to
conventional histologic examination compare with the pathologist looking at the piece of
tissue through a microscope makes the diagnosis.
The Optical measurements provide quantitative optical property values that reflect changes
in tissue perfusion, oxygen consumption, and cell/matrix development. Each measurement
requires less than 5 minutes to execute. The measurements will be taken before and after
skin treatment.This non-invasive, non-contact technique has great potential as a means to
diagnose different skin problems without the need to obtain a piece of tissue from the skin.
- Male or female age > 18 years
- current participation in any other investigational drug evaluation
- inability to understand and carry out instructions
John S Nelson, M.D,Ph.D
Beckman Laser Institue, University of California Irvine