Expired Study
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Irvine, California 92612


Purpose:

The purpose of this study is to do determine the changes in physiological and optical properties in healthy pre-menopausal breast tissue during the menstrual cycle using Diffuse Optical Spectroscopy. The Researcher can determine 1) how large variations in breast tissue components are 2) how predictable and repeatable these variations are 3) the effects of endogenous hormones on breast tissue physiology.


Study summary:

Variations in breast physiology due to hormonal fluctuations during the menstrual cycle can correlate to quantitative changes in Diffuse Optical Spectroscopy functional parameters such as hemoglobin, lipid and water concentration and tissue scattering. Diffuse Optical Spectroscopy imaging can show increase blood flow in breast tissue after ovulation with a concomitant increase in mitotic activity, changes in hemoglobin concentration and in tissue scattering. Increases in fibroglandular breast tissue after ovulation have also been observed. Diffuse Optical Spectroscopy imaging can determine after time of ovulation has been detected during the two months of self-monitoring.


Criteria:

Inclusion Criteria: - Pre-Menopausal female 18 years of age or older with normal breast tissue - Undergoes regular menstrual cycle cycles that do not vary by more than 5 days Exclusion Criteria: - Peri-Menopausal and Post-Menopausal - Subjects taking oral contraceptives or any birth control medications in the past six months - Diagnosed with breast cancer or cancer survivor,a history of breast surgery - Subjects taking light sensitive drugs for photodynamic therapy


NCT ID:

NCT00540306


Primary Contact:

Principal Investigator
Bruce J Tromberg, Ph.D
Beckman Laser Institute University of California Irvine


Backup Contact:

N/A


Location Contact:

Irvine, California 92612
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: August 17, 2017

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