Expired Study
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Cleveland, Ohio 44195


Purpose:

This study enrolled men with prostate cancer who had failed hormone therapy (as shown by rising prostate-specific antigen [PSA] levels) and who were about to start a new line of chemotherapy. Blood was drawn prior to the patient receiving chemotherapy and then monthly thereafter for up to 18 months or until disease progression, whichever occurred first. The blood was tested to find circulating tumor cells (CTC) and to count them. The circulating tumor cell levels were studied in relation to the patient's overall survival. Serum was also collected for PSA testing, and additional blood samples were drawn to test for circulating endothelial cells and RNA was isolated for future gene expression testing.


Criteria:

Inclusion Criteria: - Age > or = 18 years - Pathological diagnosis of adenocarcinoma of the prostate - First or later line of chemotherapy - Serum testosterone < 50ng/mL - ECOG 0-2 - Serum PSA > or = 5ng/mL - PSA progression (2 rises above a reference value) - Bone scan within 60 days of enrollment - Computed tomography (CT) scan - If measurable disease, bone scans every 6-8 months Exclusion Criteria: - Systemic radiation - Prior history of other carcinoma within the last 5 years, except non-melanoma skin cancer - Brain metastases


NCT ID:

NCT00133900


Primary Contact:

Principal Investigator
Ken Pienta, MD
University of Michigan


Backup Contact:

N/A


Location Contact:

Cleveland, Ohio 44195
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: December 11, 2017

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