This study will examine whether platelet gel positively affects wound healing. Platelet gel
will be used to treat punch biopsy wounds and the results will be compared to results from
wounds treated with a control treatment.
Platelets contribute to the healing process in soft tissue by providing the initial
hemostasis that occurs following injury, a framework for fibrin matrix formation and
contribution of growth factors.
According to the US National Institutes of Health, surgical procedures are considered a form
of controlled injury, so many of the complications faced by surgery patients are very
similar to those faced by trauma patients. Scientists are currently investigating ways to
treat wounds caused by trauma, burns or surgical inventions with biological agents (i.e.
growth factors) or new drugs. Growth factor priming of acute wound sites pre-activates the
cellular and molecular components of tissue repair, prior to tissue injury.
Objectives are aimed at gathering information to establish evidence that autologous platelet
gel positively effects the healing of acute wounds.
- Normal volunteers
- 18 years old or older
- Pregnant or lactating
- Diabetic, keloid former, collagen vascular disease
- Body mass index >30kg/m2
- Known history of HIV/AIDS; Hepatitis A, B, or C
- Bleeding disorder
- Aspirin, non-steroidal anti-inflammatory drug (NSAID) or anticoagulant user
- Cancer, or treatment for cancer, in past 5 years