Expired Study
This study is not currently recruiting Study Participants on ClinicalConnection.com. If you would like to find active studies please search for clinical trials.

Baltimore, Maryland 21287


Purpose:

This is a prospective study to determine whether the Atkins diet reduces seizures, creates ketosis, and is well tolerated in adults with epilepsy. Approximately 30 patients will be enrolled, expecting 20 to complete the 6-month study. The investigators plan to establish the seizure baseline and type, initiate the Atkins diet, then monitor its administration in terms of seizure reduction, ketosis, and side effects for a 6-month period.


Study summary:

Patients are seen in the Johns Hopkins General Clinical Research Center (GCRC) and started on a modified Atkins diet (15g/day of carbohydrates). Medications remain unchanged and labs are drawn. Followup is at 1 month, 3 months, and 6 months into the study. After 1 month, carbohydrates and medications can be altered. Ketosis (urine) is measured by patients semiweekly, weight weekly, and seizures daily and recorded on a calendar. This study is ongoing with approximately 20 patients of 30 enrolled as of February 2006.


Criteria:

Inclusion Criteria: - Ages 18 and over - Weekly seizures or 4 times per month - Use of at least 2 anticonvulsant drugs Exclusion Criteria: - Prior use of the Atkins diet for > 1 week - Prior use of the ketogenic diet within the past year - Kidney, heart disease, renal disease - Hypercholesterolemia - Pseudoseizures - Pregnancy - Body mass index (BMI) below 18.5 - Status epilepticus within the past 6 months - 2 week seizure-free period within the past 6 months


NCT ID:

NCT00121927


Primary Contact:

Principal Investigator
Eric H Kossoff, MD
Johns Hopkins Medical Institutions


Backup Contact:

N/A


Location Contact:

Baltimore, Maryland 21287
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: December 14, 2017

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.


Click to view Full Listing

This study is not currently recruiting Study Participants on ClinicalConnection.com. The form below is not enabled.