Age-Related Macular Degeneration (AMD) is a degenerative disease of the retina that causes a
progressive loss of central vision. AMD is the leading cause of legal blindness among
adults age 50 or older in the Western world. AMD presents in two different types - "dry"
and the more severe "wet" form. Wet AMD is caused by the growth of abnormal blood vessels
in the macula.
Squalamine lactate is an investigational drug that may prevent the growth of these abnormal
blood vessels. This study will test the safety and efficacy of Squalamine when administered
with verteporfin therapy in patients with "wet" AMD.
- Patients with a diagnosis of "wet" age-related macular degeneration
- Prior treatment for "wet" age-related macular degeneration