Expired Study
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Durham, North Carolina 27703


This trial will treat patients previously treated for advanced (metastatic) melanoma (skin cancer) with a new chemotherapeutic medicine. The new chemotherapy will be administered weekly in cycles of three weekly doses followed by one week rest. A minimum of three cycles of therapy will be given to determine the anti-tumor response of the new chemotherapy. Patients may continue to stay on therapy a maximum of 9-12 cycles if treatment shows continuing benefit.


Inclusion Criteria: - Confirmed Metastatic Melanoma - At least 18 years old - No other active malignancy - Hemoglobin at least 9 - Platelet Count at least 100,000 cells/mm3 - ANC at least 1500 cells/mm3 - AST & ALT less than 2.5X upper limit of normal - Total bilirubin less than 1.5mg/dL - Creatine less than 1.5 mg/dL - Alkaline phosphatase less than 2.5X upper limit of normal - Life expectancy of at least 12 weeks - ECOG performance status of 0-1 - Patient must provide informed consent - Patient must provide authorization to disclose Exclusion Criteria: - Evidence of active brain metastases - The only evidence of metastasis is lytic or blastic bone metastases - Pre-existing peripheral neuropathy of NCI Toxicity Criteria Scale of grade greater than 2 - Received radiotherapy in last 4wks, except if to a non-target lesion only - Clinically significant concurrent illness - Investigator's opinion that patient unlikely to complete study - Cytotoxic chemotherapeutic agent treatment or investigational drug within previous 4wks - History of allergy/hypersensitivity to study drug - Serious Medical Risk Factors determine by the investigator



Primary Contact:

Study Director
Michael Hawkins
Abraxis BioScience, LLC.

Backup Contact:


Location Contact:

Durham, North Carolina 27703
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: June 25, 2018

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