Expired Study
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New York, New York 10021


Purpose:

A clinical trial designed to compare the safety and iron excretion properties of desferoxamine (DFO) and deferitrin (GT56-252), an experimental oral iron chelator.


Criteria:

Inclusion Criteria: - Beta-thalassemia patients, 18 years of age or older, currently undergoing chronic blood transfusion therapy and iron chelation therapy who weigh more than 40 kg. - No clinically significant findings on physical exam, medical history, or screening laboratories. - Serum ferritin greater than 500 ng/mL, serum creatine creatinine within the normal range and platelet count greater than 100,000/mm3. - Willing and able to discontinue DFO or L1 for the period of study. - Woman of child-bearing potential must have a negative serum pregnancy test at screening and use a medically acceptable form of birth control during the study and for 1 month afterward. Male patients must also use barrier contraceptives during the study and for 1 month afterward. - Have a level of understanding and willingness to cooperate with the confinement and all procedures. Able to provide voluntary signed/dated written informed consent. Exclusion Criteria: - Serious medical condition unrelated to Beta-Thalassemia. - Participation in a previous investigational drug study within 30 days preceding screening. - Patients with a known allergy to DFO that prevents chronic administration.


NCT ID:

NCT00069862


Primary Contact:

N/A


Backup Contact:

N/A


Location Contact:

New York, New York 10021
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: December 12, 2017

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