The purpose of the study is to determine if black cohosh extract (BCE) administration in
symptomatic postmenopausal women results in estrogenic stimulation of the breast, as
determined by estradiol, pS2, FSH, LH, and PSA levels in nipple aspirate fluid.
- Postmenopausal females
- 20 months since any breastfeeding
- Active postmenopausal symptoms, i.e., hot flashes
- At least 6 months since last menstrual period or have had a hysterectomy with both
- Able to make 4 visits during the trial to the study clinic in Columbia, Missouri