Expired Study
This study is not currently recruiting Study Participants on ClinicalConnection.com. If you would like to find active studies please search for clinical trials.

Goldsboro, North Carolina 27534


Purpose:

RATIONALE: Genetic studies may help in understanding the genetic processes involved in the development of some types of cancer. PURPOSE: Clinical trial to study the cancer-related genes in patients who have colon cancer or adenomatous polyps.


Study summary:

OBJECTIVES: - Identify human colon neoplasia susceptibility genes in patients with colon cancer or adenomatous polyps. - Correlate the inheritance of novel susceptibility alleles for adenomatous polyposis of the colon with colon neoplasia in these patients. - Correlate colon neoplasia susceptibility with the presence of COX-2, sPLA2, and DNMT genes in these patients. - Identify a novel gene that governs increased susceptibility to colon adenoma and cancer in the genome of these patients.


Criteria:

DISEASE CHARACTERISTICS: - Diagnosis of colon cancer or polyps at age 70 or under - Has a living full sibling with diagnosis of colon cancer or polyps at age 70 or under - No history of familial adenomatous polyposis syndrome - No hereditary nonpolyposis colon cancer, according to Amsterdam criteria - No known I1370K adenomatous polyposis of the colon susceptibility variant - Enrolled on 1 of the following clinical trials: - CLB-9581 - CLB-89803 - CLB-80001 NOTE: Patients do not need to be receiving protocol therapy. Patients who are outside the treatment protocol's follow-up range are eligible. Patients who discontinued therapy for any reason, including toxic effects, are eligible. PATIENT CHARACTERISTICS: Age - 70 and under at diagnosis Other - No significant psychiatric illness that would preclude giving informed consent - No inflammatory bowel disease (in patient or sibling)


NCT ID:

NCT00055848


Primary Contact:

Study Chair
Monica M. Bertagnolli, MD
Dana-Farber/Brigham and Women's Cancer Center


Backup Contact:

N/A


Location Contact:

Goldsboro, North Carolina 27534
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: December 18, 2017

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.


Click to view Full Listing

This study is not currently recruiting Study Participants on ClinicalConnection.com. The form below is not enabled.