The purpose of this study is to develop an effective treatment for people with Post
Traumatic Stress Disorder (PTSD) along with other mental illnesses.
Despite the progress in treating PTSD in the general population and the elevated prevalence
of PTSD in people with severe mental illness (SMI), there are no empirically validated
treatments designed for patients with comorbid PTSD. The cognitive behavioral treatment
provided in this study may improve knowledge of PTSD, decrease distorted beliefs, reduce
PTSD symptoms, and improve quality of life.
Participants are randomly assigned to receive either a cognitive behavioral treatment plus
standard care for SMI or standard care alone. The cognitive behavioral treatment
incorporates several common features, including psychoeducation, relaxation training, and
cognitive restructuring. Standard care for SMI includes medication, case management, and
psychosocial treatment. PTSD, psychiatric symptoms, health, quality of life, and substance
abuse outcomes are measured. Participants' knowledge of PTSD and beliefs about the world are
also measured. Participants are assessed at baseline, post-treatment (16 weeks), and at 3-
and 6-month follow-ups.
For information on a related study, please follow this link:
- Post Traumatic Stress Disorder
- New Hampshire definition of SMI plus DSM-IV Axis I diagnosis of schizophrenia,
schizoaffective disorder, bipolar disorder, or major depression
- Case management services and contact with a case manager at least twice a week
- Alcohol or drug dependence
- Hospitalization or suicide attempt in the past 2 months