To examine the role of outdoor pollen grains and fungal spores in the exacerbation of asthma
and to produce forecasting models to predict days of high concentration.
Asthma is a growing problem, and outdoor allergens play a role in exacerbation of many
cases. A clearer understanding of this role and its magnitude, and a means of controlling
the effects of outdoor allergen exposures is needed. We propose Poisson time-series and
conditional panel studies to test these hypotheses: 1) The incidence of acute asthma
attacks, as measured by urgent care inhalation treatments and hospitalizations for asthma,
has a dose-dependent relationship with exposure to specific outdoor allergens; 2) Specific
sensitization to outdoor allergens is a risk factor for having an acute attack; and 3)
Exposure conditions that lead to acute asthma attacks can be forecast, creating an
opportunity to reduce asthma morbidity and mortality ny targeting pretreatment and/or
Must be a member of the Fallon HMO and be treated for acute asthma exacerbation.