To determine cell cycle parameters and changes after treatment, the labelling agent is given
and a bone marrow aspiration is accomplished before treatment and after treatment for
comparison. Participants must be undergoing concurrent therapy for hematologic malignancy.
Cell cycle parameters include LI, Ts, Tc, T dpot, changes in these parameters, and
differences between normal and leukemic cells in patients with hematologic malignancy prior
to and following treatment.
Histologic proof of one of:
- AML, ALL, or AUL
- MDS or CMML
- OR undergoing bone marrow transplantation.
Participants should be:
- off therapy for at least two weeks
- At least 18 years old or older
- Using adequate contraception if of child-bearing capability.