Expired Study
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Houston, Texas 77030


Purpose:

For patients with relapsed and refractory aggressive non-Hodgkin's lymphoma


Criteria:

INCLUSION: - Bidimensionally measurable current/refractory aggressive NHL (Diffuse lg cell, diffuse mixed cell, follicular lg non-cleaved, immunoblastic, Ki-1+ALCL, peripheral T-cell lymphoma, mantle cell lymphoma & transformed lymphoma.) - No more than 3 prior treatment regimens. No anti-lymphoma therapy within the past 3 weeks. - Not be eligible for treatment of a higher priority. - Performance status <2 Zubrod, > 60 Karnofsky. - Good marrow reserve: ANC>1.5 x 10(9)/L, platelets > 100 x 10(9)/L. - Bilirubin <1.5mg/dL, SGOT, SGPT < 2 x normal values. - Serum creatinine < 1.8 mg/dL. - Age > 18 yrs. - Signed informed consent. - Life expectancy of > 12 weeks. - No prior Taxane (paclitaxel or docetaxel), topotecan, or CPT-11. - No prior stem cell or bone marrow transplantation. - No prior second malignancies except for basal cell carcinoma of the skin. EXCLUSION: - Active or prior history of CNS lymphoma. - Serious intercurrent medical illnesses requiring hospitalization. - History of primary/secondary immunodeficiency (other than related to the malignant lymphoma because treatment is dependent on a functional immune system) or patients taking immunosuppressive drugs (systemic corticosteroids). - Prior exposure to Filgrastim-SD/01. - Women who are pregnant or lactating. - Participation in another clinical trial. - Positive HIV antibody. - History of prior sensitivity to E. coli derived products (such as filgrastim/neupogen).


NCT ID:

NCT00038545


Primary Contact:

Principal Investigator
Anas Younes, MD
UT MD Anderson Cancer Center


Backup Contact:

N/A


Location Contact:

Houston, Texas 77030
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: December 12, 2017

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