Expired Study
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Houston, Texas 77030


Purpose:

A Pilot Study of Transfusion of rhTPO-Derived Autologous Platelets Cryopreserved with ThromboSol and 2% DMSO in Patients with Gynecologic Malignancy Receiving Carboplatin


Criteria:

INCLUSION CRITERIA: - Patients with gynecologic malignancy for whom treatment with carboplatin is indicated. - Age >/= 15 years. - Adequate hematologic, renal, and hepatic functions. - Life expectancy >/- 3 months. Karnofsky Performance Status >/= 80. - Signed informed consent form. EXCLUSION CRITERIA: - Patients with rapidly progressive disease. - Pregnant or lactating women. - Patients with comorbid condition which renders patients at high risk of treatment complication. - History of CNS metastasis. - Patients with significant cardiac disease (NYHA Class III or IV), dysrhythmia, or recent history of MI or ischemia, transient ischemic attack or CVA within the 6 months of study entry. - Prior chemotherapy, immunotherapy, any experimental drug within 4 weeks, use of myeloid (G-CSF or GM-CSF) growth factors within 2 weeks or erythropoietin within 4 weeks. - Use of any nitrosourea (BCNU, CCNU) or mitomycin - C within 6 weeks. - Prior surgery or RT within 2 wks of study entry. - Patients with history of prior high dose chemotherapy with stem cell transplant or with history of prolonged thrombocytopenia (> 2 weeks). - History of leukemia. - History of any platelet disorders including ITP, TTP or bleeding disorders. - History of > 3 prior chemotherapy regimens (all platinum regimens will be counted as 1 regimen). - Demonstrated lack of response to platinum-based therapy.


NCT ID:

NCT00038012


Primary Contact:

Study Chair
Saroj Vadhan-Raj, MD
UT MD Anderson Cancer Center


Backup Contact:

N/A


Location Contact:

Houston, Texas 77030
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: December 17, 2017

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