The purpose of this study is to conduct a drug interaction study with NS2359 and cocaine in
cocaine experienced volunteers.
This is a single-center, double-blind, placebo-controlled, randomized, single dose, fixed
order, dose escalating inpatient design that will study oral NS2359 in cocaine experienced
Male or Female, 18-45 yrs of age; females of child-bearing potential using appropriate
method of birth control; be able to understand the procedure and agrees to participate via
informed consent; must be cocaine dependent according to DSM-4 criteria; must be capable
of providing written consent; must be able to comply with protocol requirement, CPU rules
and regulations; must not be currently seeking treatment for cocaine abuse.
Incapable of understanding the informed consent process; Additional criteria available
during screening at the site.