Expired Study
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Minneapolis, Minnesota 55417


Purpose:

The purpose of this study is to determine how people with high triglycerides metabolize and absorb bile acids, compounds made in the body from cholesterol. This project has two objectives: A) To define the mechanism of impaired bile acid absorption in hypertriglyceridemia (specifically we will determine if the active or passive component of absorption is abnormal) and B) to determine the contribution of an alternative pathway of bile acid synthesis which begins with 27-hydroxylation of cholesterol. Because 27-hydroxylase is present in endothelial cells as well as liver, this pathway may play a role in removal of cholesterol from incipient atherosclerotic plaque.


Criteria:

Hypertriglyceridemia and normal controls with normal lipids


NCT ID:

NCT00018720


Primary Contact:

Norman Javitt, M.D.


Backup Contact:

N/A


Location Contact:

Minneapolis, Minnesota 55417
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: September 19, 2017

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