This study will determine baseline language skills in children 4 to 8 years old. The data
will be used to design studies using functional magnetic resonance imaging (fMRI) to
identify what areas of the brain in children are involved in understanding language. This
information is important for children who require brain surgery to control seizures.
Healthy normal volunteers between the ages of 4 and 8 years who have an IQ of 70 or more;
who have no history of neurologic, psychiatric or language disorder; who are performing at
or above grade level, and who are native English speakers may be eligible for this study.
Participants will be asked to do the following:
- name pictures or read words that appear on a computer screen
- listen to stories and answer questions about them
- match pictures to a spoken word
The children's responses will be recorded.
We propose to study normal children to establish baseline data to use to develop novel sets
of stimuli for functional imaging paradigms. Tasks using these stimuli will include object
naming, sentence comprehension, and single word reading.
Children will be between the ages 4 and 8 are eligible.
Children who meet one of the following criteria are not eligible:
IQ below 70;
History of neurologic or psychiatric disorders;
History of an language disorder;
Performing below grade-level;
Non-native English speaker.