This study is intended to help doctors learn about the relationships between specific
genetic makeup (gene markers) and the development of chronic rejection. This study is being
done to see if there is a relationship between genetic patterns and the development of
Chronic Allograft Nephropathy (CAN). Medical scientists also hope to learn more about how
genetic differences between people determine their response to a drug or a disease by
storing a small blood sample in a special "bank". This sample may be tested at some point
in the future in an attempt to better understand the factors that may influence rejection,
transplantation outcomes and transplant success rates.
- All subjects must be recipients of a renal allograft.
- Study subjects must have evidence of biopsy-proven Chronic Allograft Nephropathy
- Control subjects must not have evidence of CAN.