I. Determine the mode of inheritance of nonsyndromal Mondini inner ear dysplasia, an inner
ear malformation causing deafness, vestibular dysfunction, and recurrent meningitis.
The parents of 1 family with known Mondini dysplasia are screened for the disorder using
temporal bone computerized tomography without contrast. This information is used to
determine the mode of inheritance.
PROTOCOL ENTRY CRITERIA:
Parents of a study family with nonsyndromal Mondini dysplasia