Expired Study
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Duluth, Minnesota 55805


Purpose:

RATIONALE: Genetic studies may help in understanding the genetic processes that cause some types of cancer. PURPOSE: Genetic trial to study certain genes of patients who have stage II or stage III colon cancer.


Study summary:

OBJECTIVES: - Determine the adverse prognostic significance of 8p allelic imbalance (AI) in patients with colon cancer. - Determine if patient prognosis is dependent on the region of 8p AI. - Perform fine mapping studies to further localize the putative tumor suppressor gene(s) on 8p. - Perform multicolor FISH to examine the role that 8p loss and 8q gain play in the prognosis of patients whose tumors exhibit 8p AI. OUTLINE: Matched normal and tumor DNA is analyzed for 8p allelic imbalance with at least 8 markers: D8S262 and D8S1825 localized to 8p23, D8S254 and D8S261 at 8p22, D8S560 and D8S136 at 8p21, and D8S1820 and D8S283 at 8p12. Normal/tumor tissue pairs are used for fine mapping studies.


Criteria:

DISEASE CHARACTERISTICS: - Diagnosis of resectable stage II or III adenocarcinoma of the colon - Participated in NCCTG-914653 - DNA extracted from both normal and tumor tissue PATIENT CHARACTERISTICS: Age - Under 70


NCT ID:

NCT00003833


Primary Contact:

Study Chair
Richard M. Goldberg, MD
Mayo Clinic


Backup Contact:

N/A


Location Contact:

Duluth, Minnesota 55805
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: December 11, 2017

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