Expired Study
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New York, New York 10021


Purpose:

The purpose of this study is to see if it is safe and effective to give zintevir (AR177) to asymptomatic (no symptoms) HIV-infected patients. Zintevir belongs to a new class of anti-HIV drugs, the integrase inhibitors. HIV uses the protein integrase to infect a cell. Integrase inhibitors block integrase and may stop replication of HIV.


Study summary:

Zintevir belongs to a new class of anti-HIV drugs, the integrase inhibitors. The HIV-1 virus uses the protein integrase to incorporate its genetic material into the infected host cell. Integrase inhibitors block integrase and may stop replication of the HIV-1 virus. In this open-label, Phase I/II study, 3 groups of HIV-positive patients (12 patients total) receive escalating doses of intravenous zintevir for 14 consecutive days.


Criteria:

Inclusion Criteria You may be eligible for this study if you: - Are HIV-positive, but do not have any symptoms of HIV infection. - Have a CD4 count greater than 200 cells/mm3. - Have a viral load (level of HIV in the body) greater than 4,000 copies/ml. - Are at least 18 years old. Exclusion Criteria You will not be eligible for this study if you: - Tend to have abnormal bleeding or other blood problems. - Have an active AIDS-defining illness. - Have a history of serious disease or illness. - Abuse alcohol or drugs. - Have received certain medications.


NCT ID:

NCT00002403


Primary Contact:

N/A


Backup Contact:

N/A


Location Contact:

New York, New York 10021
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: September 20, 2017

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