Expired Study
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Laguna Hills, California 92656


Purpose:

To evaluate the effect of Isoprinosine in patients diagnosed as having AIDS relative to: Laboratory (immunologic defects): - Comparison of total helper and suppressor T-cell numbers among the groups. - Comparison of changes in natural killer cell activity. - Comparison of other laboratory findings among the groups. Clinical changes: - Comparison of the frequency of opportunistic infections among the groups. - Comparison of the frequency of the development of AIDS-related malignancies. - Comparison of other clinical manifestations relative to severity and time of onset.


Criteria:

Exclusion Criteria Co-existing Condition: Patients with a history of gout, urolithiasis, nephrolithiasis, renal dysfunction, and severe gastric ulcer are excluded. Concurrent Medication: Excluded: - Steroids. - Cytotoxic immunosuppressive agents. - Radiotherapy. The following are excluded: - Critically ill patients. - Patients receiving steroids, cytotoxic immunosuppressive agents, radiotherapy. - Patients who have received any other immunotherapy. - Patients with a history of gout, urolithiasis, nephrolithiasis, renal dysfunction, and severe gastric ulcer. Prior Medication: Excluded: - Any other immunotherapy. Patients with severe AIDS and specified laboratory immunologic defects.


NCT ID:

NCT00002295


Primary Contact:

N/A


Backup Contact:

N/A


Location Contact:

Laguna Hills, California 92656
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: September 20, 2017

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