Expired Study
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Baltimore, Maryland 21205


Purpose:

To determine whether zidovudine (AZT) in conjunction with bone marrow transplantation prevents the reinfection of donor hematopoietic/lymphoid cells in patients with positive HTLV III antibody and large cell/diffuse histiocytic lymphoma. Patients who are candidates will be evaluated for HTLV III activity and drug levels.


Criteria:

Exclusion Criteria Co-existing Condition: Patients with current life-threatening infection at time of transplant that would preclude a transplant are excluded. Concurrent Medication: Excluded: - Other anti-retroviral agents. Patients with current life-threatening infection at time of transplant that would preclude a transplant are excluded. Patients must be: - HTLV III antibody positive by ELISA or Western blot or HTLV III viremia. - At high mortal risk with a diagnosis of AIDS or AIDS Related Complex (ARC). - Also patient must fall into one of the following categories: - Have an HIV seronegative identical twin to serve as a bone marrow donor. - Have documentation of large cell/diffuse histiocytic lymphoma/DPDL. - Be a good risk candidate for bone marrow transplant.


NCT ID:

NCT00002284


Primary Contact:

N/A


Backup Contact:

N/A


Location Contact:

Baltimore, Maryland 21205
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: September 20, 2017

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