The purpose of this study is to test the belief that specific areas of the brain are
connected differently in blind patients than patients with sight. In addition, the study
will examine the different anatomical connections between brain areas of patients who became
blind early in life versus patients who became blind later.
The purpose of this protocol is to test the hypothesis that the anatomical connectivity of
occipital and somatosensory areas in early blind subjects differs from that in subjects who
became blind later in life and from that in sighted volunteers.
Subjects with late blindness.
Subjects with early blindness.
Age between 18 and 65 years.
Subjects with personal or family history of seizures or other neurological or
Pregnant women tested after urine pregnancy test.
Subjects with metal in the cranium except mouth.
Subjects with intracardiac lines and implanted medication pumps.
Subjects with increased intracranial pressure as evaluated by clinical means.
Subjects with cardiac pacemakers.
Intake or neuroleptics.
Subjects with blindness secondary to degenerative CNS diseases.