Bethesda, Maryland 20892


The goal of this study is to diagnose and follow patients with disorders of movement control. Patients participating in this study will undergo routine laboratory tests and examinations in order to monitor their condition. Doctors at the NIH will work in cooperation with each patient's primary care physician. There will be no use of investigational treatments in this study.<TAB>

Study summary:

Objective: This protocol is a screening protocol, which allows for evaluation of patients and families where neurological conditions are present for enrollment into other studies. It is also a teaching and training instrument for the MNB fellows, allowing them to gain expertise in the evaluation and treatment of patients. Study population: Subjects with neurological disorders or a family member with a neurological disorder may be eligible to undergo a clinical evaluation. Subjects must be 2 years old or older. National Institutes of Health (NIH) employees (other than those employed by HMCS in NINDS) may participate. Design: The goal is to screen patients with neurological conditions and family members of patients with neurological conditions for enrollment in additional research protocols. No investigational treatments will be administered on this protocol and the NIH physicians will be playing a consultative role to the patient s primary physician. Outcome measures: This is a natural history screening protocol to evaluate patients with neurological disorders and their family members. Therefore, there is no outcome measure.


- INCLUSION CRITERIA: Patients with neurological disorders and subjects with a family history of neurological conditions. EXCLUSION CRITERIA: - Patients <2 years old. - Employees of HMCS in NINDS. EXCLUSION CRITERIA FOR MRI: We will follow the Clinical Radiology/NMR Center guidelines for MR safety. Some of the exclusions are: - Have non-MRI compatible metal in the body, such as a cardiac pacemaker, brain stimulator, shrapnel, surgical metal, clips in the brain or on blood vessels, cochlear implants, artificial heart valves or metal fragments in the eye as these make having an MRI unsafe. - Have metallic dental fillings which are likely to cause MRI artifacts - Unable to lie flat on the back for the expected length of the experiment, up to 30 mins. - Uncomfortable being in a small space for the expected length of the experiment, up to 30 mins. - Pregnancy.



Primary Contact:

Principal Investigator
Mark Hallett, M.D.
National Institute of Neurological Disorders and Stroke (NINDS)

Elaine P Considine, R.N.
Phone: (301) 435-8518

Backup Contact:

Mark Hallett, M.D.
Phone: (301) 496-9526

Location Contact:

Bethesda, Maryland 20892
United States

For more information at the NIH Clinical Center contact Patient Recruitment and Public Liaison Office (PRPL)
Phone: 800-411-1222

Site Status: Recruiting

Data Source:

Date Processed: September 19, 2017

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