The purpose of this study is to determine the effect of nefazodone on relapse to cocaine use
in depressed and non-depressed females with cocaine abuse/dependence.
The purpose of this study is to determine the effect of nefazodone on relapse to cocaine in
women and if a greater effect will be seen in the dependent condition. A relapse and coping
skills questionnaire will be utilized to determine the various factors important to the
Female, ages 18-55, cocaine abuse/dependence, use of cocaine 7 days of the last 30 days or
of the 30 days prior to current abstinence, less than 90 days current abstinence, at least
an 8th grade education.
Unstable medical conditions; current use of Hismanal, Seldane, or Propulsid; dx of MR,
OBS, bipolar, schizophrenia.