The purpose of this study is to determine the effects of nefazedone on cocaine
self-administration in depressed and non-depressed female cocaine users.
This study evaluated the effect of nefazodone on reducing cocaine use and craving in both
depressed and nondepressed women and if there was a greater effect in depressed women.
Females, ages 18-55, minimum use of 8 days of the last 30, minimum of 8th grade education,
current diagnosis of cocaine abuse/dependence
Unstable medical illness, dx of MR, OBS, bipolar