The purpose of this study is to conduct experiments to examine subjective and reinforcing
effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug
abusers and preference procedures will be used to assess reinforcing effects. Comparisons
between nitrous oxide, opiates, and benzodiazepine antagonists will be made. To examine
sevoflurane versus isoflurane inhalation at subanesthetic concentrations on mood, pain, and
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