The purpose of this study is to evaluate the effects of IV dynorphin in humans during acute
heroin abstinence, in order to determine that dynorphin suppresses acute opiate withdrawal,
reduces opiate craving, and is safe at doses required to produce the above effects.
Randomized double blinded study of the effects of a single IV dose of dynorphin A 1-13 on
heroin withdrawal in human opiate addicts
opiate addict between the ages of 18-55
Regular abuse of other drugs, unstable medical conditions