The purpose of this study is to explore ways to cross patients over from methadone to
M/F ages 21-50. Opiate dependence according to DSM-IV critera. Self-reported use within
the last 30 days. Agreeable to conditions of study and signed informed consent.
Psychiatric disorder that requires medication therapy. History of seizures. Pregnant
and/or nursing women. Dependence on ETOH or benzodiazepines or other sedative-hynotics.
Acute hepatitis. Other medical conditions that deem participation to be unsafe.