Mindfulness-Oriented Recovery Enhancement for Chronic Pain Patients Receiving Opioid Therapy: Exploration of Cognitive, Affective, and Physiological Mechanisms
| City: |
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Tallahassee |
| State: |
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Florida |
| Zip Code: |
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32306 |
| Conditions: |
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Chronic Pain - Opioid Abuse, Unspecified Use |
| Purpose: |
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Persons suffering from chronic pain who are treated with long-term opioid therapy are at
risk of misusing prescription opioids and developing opioid addiction. Moreover, long-term
use of opioids may result in hyperalgesia, which exacerbates opioid craving and consumption.
Mindfulness interventions have been shown reduce chronic pain symptoms, addictive processes,
and substance use. The investigators hypothesize that relative to a support group control
condition, participation in a novel mindfulness-oriented cognitive intervention,
Mindfulness-Oriented Recovery Enhancement (MORE), will result in improved well-being and
decreased pain, opioid craving, and opioid misuse behaviors among chronic pain patients
receiving opioid therapy.
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| Study Summary: |
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Few behavioral treatments target the cognitive-affective mediators of opioid misuse and
addiction in chronic pain patients. As such, novel, multimodal interventions are needed to
effectively target key mechanisms in the risk chain from chronic pain to opioid misuse and
addiction. The secondary aim of this study is to explore possible cognitive, affective, and
psychophysiological mediators of intervention effects on pain, opioid craving, opioid misuse
behaviors, and well-being.
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| Criteria: |
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Inclusion Criteria:
- chronic pain diagnosis (ICD-9 diagnoses 338.xx)
- treatment with prescription opioids for > 3 months
Exclusion Criteria:
- prior mindfulness training
- persons who are experiencing acute opioid withdrawal
- suicidal ideation
- psychosis
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| NCT ID: |
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NCT01505101 |
| Primary Contact: |
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Principal Investigator
Eric L Garland, PhD
Florida State University
Eric L Garland, PhD
Phone: 850-645-9571
Email: egarland@fsu.edu
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| Backup Contact: |
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N/A |
| Location Contact: |
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Tallahassee, Florida 32306
United States
Eric L Garland, PhD
Phone: 850-645-9571
Email: egarland@fsu.edu
Site Status: Recruiting |
| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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May 20, 2013 |
| Modifications to this listing: |
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