Prevention of Infection in Surgical Treatment of Closed Fractures: A Comparative Study of Cefazolin Versus Vancomycin

Conditions:		Closed Fractures
Purpose:		With the growing incidence of MRSA in the hospital and community setting it would be hypothesized that Vancomycin would decrease the risk of infection in patients requiring surgical treatment of closed fracture as compared to Cefazolin.
Study Summary:
Criteria:		Inclusion Criteria: Over 18 years of age or less than 85 years of age Ability to understand and agree to informed consent Qualifying fracture requiring surgical intervention on one day. Exclusion Criteria: under 18 years of age or older than 85 years of age Unable to understand and agree to informed consent Documented allergy to Cefazolin or Vancomycin Use of antibiotics within 2 weeks before or after injury Previous of MRSA infection Fractures requiring multiple operations on various days Previous surgery on the injured extremity within 1 year
NCT ID:		NCT01029457
Primary Contact:		Principal Investigator Peter J Nowotarski, MD University of Tennessee Jeremy Bruce, M.D. Phone: 423-778-9202 Email: bruce_jeremy@hotmail.com
Backup Contact:		Email: elaine.pugh@erlanger.org Elaine Pugh Phone: 423-778-5663
Location Contact:		Chattanooga,, Tennessee 37403 United States Joseph N Rudd, PhD Phone: 423-778-6072 Email: joe.rudd@erlanger.org Site Status: Recruiting

Data Source:		ClinicalTrials.gov
Date Processed:		May 23, 2013
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