View Clinical Trial (Medical Research Study)
Safety and Efficacy of Cervical Sympathetic Block in Patients With Cerebral Vasospasm Following Aneurysmal Subarachnoid Hemorrhage - Pilot Study
| City: |
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Seattle |
| State: |
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Washington |
| Zip Code: |
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98104 |
| Conditions: |
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Severe Vasospasm |
| Purpose: |
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To evaluate the feasibility of performing a cervical sympathetic block in patients with
severe cerebral vasospasm involving the anterior cerebral circulation following aneurysmal
SAH.
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| Study Summary: |
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| Criteria: |
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Inclusion Criteria:
1. High grade spontaneous SAH (Fisher Grade III and IV)
2. Secured aneurysm (clipped/coiled)
3. Evidence of severe vasospasm - MCA mean flow velocity >200 cm/sec and Lindegaard
ratio >6 OR Symptomatic vasospasm with either angiographic evidence (no angioplasty),
or at least moderate severity according to TCD criteria (MCA mean flow velocity >150
cm/sec and Lindegaard ratio >3, or ACA vasospasm)
4. Age ≥18
Exclusion Criteria:
1. Allergy to local anesthetic or contrast
2. Coagulation disorders with PT <70%, or INR >1.4, or PTT >1.5 times control and/or
platelets <70,000x106/L
3. Use of enoxaparin within 12 hours
4. Use of clopidogrel within 7 days
5. Use of coumadin within 5 days
6. Use of ticlopidine within 14 days
7. Use of intravenous thrombolytics within 10 days
8. Any use of hirudin derivatives during ICU stay
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| NCT ID: |
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NCT00930072 |
| Primary Contact: |
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Principal Investigator
Miriam Treggiari, MD
University of Washington
Miriam Treggiari, MD
Phone: 206-744-4687
Email: treggmm@u.washington.edu
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| Backup Contact: |
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Email: lsissons@uw.edu
Laura Sissons-Ross
Phone: 206-744-5992
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| Location Contact: |
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Seattle, Washington 98104
United States
There is no listed contact information for this specific location.
Site Status: Recruiting |
| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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June 18, 2013 |
| Modifications to this listing: |
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